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The antibody targeting platelet-derived growth factor receptor alpha (PDGFRA), olaratumab, was approved in 2016 for metastatic soft tissue sarcoma (STS) in combination with doxorubicin based on promising results of a phase Ib/II trial by the Food and Drug Administration (FDA). | Combination therapy with Olaratumab doxorubicin in advanced or metastatic soft tissue sarcoma - a single-Centre experience