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Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations

Invasive cribriform and intraductal carcinoma (CR/IDC) is associated with adverse outcome of prostate cancer patients. The aim of this study was to determine the molecular aberrations associated with CR/IDC in primary prostate cancer, focusing on genomic instability and somatic copy number alterations (CNA). | Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations