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Development of an oncogenic dedifferentiation SOX signature with prognostic significance in hepatocellular carcinoma

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Gradual loss of terminal differentiation markers and gain of stem cell-like properties is a major hall mark of cancer malignant progression. The stem cell pluripotent transcriptional factor SOX family play critical roles in governing tumor plasticity and lineage specification. | Development of an oncogenic dedifferentiation SOX signature with prognostic significance in hepatocellular carcinoma

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