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Absence of an embryonic stem cell DNA methylation signature in human cancer

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Differentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture of cell types that are of fetal origin and are reminiscent of embryonic stem cell lineage. | Absence of an embryonic stem cell DNA methylation signature in human cancer

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