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Spatial heterogeneity of prostate cancer-specific mortality in Pennsylvania remains unclear. We utilized advanced geospatial survival regressions to examine spatial variation of prostate cancer-specific mortality in PA and evaluate potential effects of individual- and county-level risk factors. Methods: Prostate cancer cases, aged ≥40 years, were identified in the 2004 | Spatial patterns in prostate Cancer-specific mortality in Pennsylvania using Pennsylvania Cancer registry data 2004 2014