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Pyrazolines show different biological activities. In recent years, interest in the chemistry of hydrazonoyl halides has been renewed. 1,3,4-Thiadiazoles are one of the most common heterocyclic pharmacophores with a wide range of biological activities. | Utility of 5 - furan-2 -yl -3 - p- tolyl -4 5-dihydro -1H- pyrazole-1-carbothioamide in the synthesis of heterocyclic compounds with antimicrobial activity