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Synthesis of acyl oleanolic acid-uracil conjugates and their anti-tumor activity

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Oleanolic acid, which can be isolated from many foods and medicinal plants, has been reported to possess diverse biological activities. It has been found that the acylation of the hydroxyl groups of the A-ring in the triterpene skeleton of oleanolic acid could be favorable for biological activities. The pyrimidinyl group has been con‑ structured in many new compounds in various anti-tumor studies. | Synthesis of acyl oleanolic acid-uracil conjugates and their anti-tumor activity

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