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Pyogenic infections are one of the major complications of surgery and trauma. Both aerobic and anaerobic bacteria have been implicated in these infections which commonly occur under hospital environment resulting in significant morbidity, prolonged hospitalization and huge economic burden. Hence periodical monitoring of bacterial profile and their antibiotic susceptibility pattern is important. A retrospective study was undertaken to identify the microbial profile with their antibiogram among the pus culture isolates in a teaching tertiary care hospital from January 2018 to December 2018. 171 pus culture samples processed at the microbiology lab were analyzed. The isolates from positive pus culture were identified by standard protocols and antimicrobial susceptibility patterns were identified by CLSI guidelines. Positive pus cultures were obtained in 52% (89/171). Gram positive bacteria accounted for 46.2 % (43), Gram negative bacteria 53.8% (50) and Candida spp 1.01% (1) with predominance of S. aureus 30% (28) followed by K. pneumoniae 18% (17) and E. coli 17% (16). 39.5% of S. aureus was MRSA and 100% sensitive to vancomycin. 88% of E. coli and 53% of K. pneumoniae were ESBL producers and 100% sensitive to meropenam. | Bacteriological profiles of pus with antimicrobial sensitivity pattern at a teaching hospital in Vikarabad