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Tải xuống
Matrix metalloproteinases (MMPs), produced by osteoblasts, catalyze the turnover of extracellular matrix (ECM) molecules in osteoid, and the regulation of MMP activity depends on interactions between MMPs and tissue inhibitors of metalloproteinases (TIMPs). | Tension force downregulates matrix metalloprotein-ase expression and upregulates the expression of their inhibitors through MAPK signaling pathways in MC3T3-E1 cells