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To establish a process of extracting total saponin from wild papaya leaves using ultrasonic method. Research method: Ultrasonic extraction; investigation of process parameters: herbal particles size, solvent type, solvent/material ratio, number of extraction, extraction temperature and extraction time; quantify saponin by UV-Vis method. | Study on the extraction of total saponin from folium trevesiae palmatae using ultrasonic method