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A wide range of phytochemicals are present in apple (Malus domestica Borkh), their production was accelerated when apple was subjected to biotic stress. These chemicals were measured in the leaf of apple cultivar Shireen, healthy and infected by Venturia inaequalis and examined by microscope. Scab-induced metabolic re-programming was analyzed by methanol leaf extract by using Gas Chromatography-Mass Spectrometry, while the mass spectra of the compounds found in the extract were matched with the National Institute of Standards and Technology (NIST) library. The compounds were identified by comparing their retention time and peak area with that of literature and by interpretation of mass spectra. | Metabolic studies of malus Domestica leaves infected and non-infected with Venturia inaequalis