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Food is the basic necessity of mankind. Human gastrointestinal tract resident microflora contains good bacteria that extend therapeutic benefits which are termed as Probiotics. The use of probiotics, prebiotics that stimulates probiotics and synbiotics which is a combination of pro and prebiotics improve the gut homeostasis, has been blooming for the past decade. Recent work on relevant probiotic strains has also led to the isolation and characterisation of certain probiotic derived metabolites called as postbiotics. The different forms of postbiotics include peptidoglycans; exopolysaccharides; organic acids or shortchain fatty acids, peptide molecules; and bacteriocins. These have favourable absorption, metabolism and distribution abilities which could indicate a high capacity to signal different organs and tissues in the host thus eliciting several biological responses. The incorporation of live probiotic bacteria in foods is dependent on propagation, processing steps, viability, survival number, colonization and so on. To overcome these problems their metabolites may be a good alternative to probiotics. In contrast, postbiotics are supposed to be more stable than the probiotics allowing their application in a wide variety of functional food products. | International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 8 Number 01 2019 Journal homepage http www.ijcmas.com Review Article https doi.org 10.20546 ijcmas.2019.801.214 Postbiotics - One Step Ahead of Probiotics L. Malashree Vishwanath Angadi K. Shivalkar Yadav and R. Prabha Department of Dairy Microbiology Dairy Science College KVAFSU Hebbal Bengaluru -560 024 India Corresponding author ABSTRACT Keywords Postbiotics Metabiotics and Bacterial metabolites Article Info Accepted 15 December 2018 Available Online 10 January 2019 Food is the basic necessity of mankind. Human gastrointestinal tract resident microflora contains good bacteria that extend therapeutic benefits which are termed as Probiotics. The use of probiotics prebiotics that stimulates probiotics and synbiotics which is a combination of pro and prebiotics improve the gut homeostasis has been blooming for the past decade. Recent work on relevant probiotic strains has also led to the isolation and characterisation of certain probiotic derived metabolites called as postbiotics. The different forms of postbiotics include peptidoglycans exopolysaccharides organic acids or shortchain fatty acids peptide molecules and bacteriocins. These have favourable absorption metabolism and distribution abilities which could indicate a high capacity to signal different organs and tissues in the host thus eliciting several biological responses. The incorporation of live probiotic bacteria in foods is dependent on propagation processing steps viability survival number colonization and so on. To overcome these problems their metabolites may be a good alternative to probiotics. In contrast postbiotics are supposed to be more stable than the probiotics allowing their application in a wide variety of functional food products. Introduction Food is an essential part of everyone s life. It gives us the nutrients to grow and develop be healthy and active. Human body needs all the essential nutrients .
