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Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells

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Previously, we have demonstrated that human ABCB5 is a full-sized ATP-binding cassette transporter that shares strong homology with ABCB1/P-glycoprotein. ABCB5-transfected cells showed resistance to taxanes and anthracyclines. Herein, we further screened ABCB5 substrates, and explored the mechanism of resistance. | Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells

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