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Most common bacterial agents of Lower Respiratory Tract Infection in the Intensive Care Units are Pseudomonas, Acinetobacter, Klebsiella, Citrobacter; which are multi drug resistant, and with limiting the therapeutic options.Nonfermenting Gram-negative bacilli are known to produce Extended spectrum β-lactamases (ESBLs) and metallo β-lactamases. Pseudomonas aeruginosa and Acinetobacter spp. in particular are most often associated with carbapenem resistance. | Prevalence of carbapenem resistance in nonfermenting gram negative bacteria in patients with respiratory tract infection admitted in intensive care units in tertiary care centre
