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Objectives: To analyse clinical, subclinical features of Graves’ patients indicated endoscopic surgery. Subjects and methods: A prospective study based on data of patients undergoing endoscopic thyroid surgery in National Hospital of Endocrinology from 1 - 2005 to 5 - 2017. | Journal of military pharmaco-medicine no8-2018 AN ANALYSIS OF CLINICAL, SUBCLINICAL FEATURES OF GRAVES’ PATIENTS BEFORE ENDOSCOPIC THYROID SURGERY Tran Doan Ket1; Tran Ngoc Luong1; Kieu Trung Thanh2 SUMMARY Objectives: To analyse clinical, subclinical features of Graves’ patients indicated endoscopic surgery. Subjects and methods: A prospective study based on data of patients undergoing endoscopic thyroid surgery in National Hospital of Endocrinology from 1 - 2005 to 5 - 2017. Results: Rate of goiter’s size in grade II was 88.2%. Mean volume of thyroid gland was 30.48 ± 1.15. Mean number of vessel spots was 3.42 ± 0.87. Subclinical: Serum T3 level: 1.55 ± 0.39 nmol/L, serum FT4: 17.25 ± 2.73 pmol/L, serum TSH 1.13 ± 0.92 µIU/mL. Serum TRAb: 10.48 ± 3.85 U/L. Conclusion: Clinical and subclinical examinations prior to endoscopic surgery for Graves’ patient are essential for prognosis, aiming to evaluate surgery, ensuring surgical safety. * Keywords: Grave disease; Endoscopic thyroid surgery; Subclinical and clinical features. INTRODUCTION Graves’ disease was a common autoimmune disorder in our country and all the world. In Europe, the annual incidence was 20 cases per 100,000 people. In America, this figure was 40 cases per 100.000 people. This disease was predominant in females, the incidence in female was 4 - 6 times higher than in males. The common age was from 20 to 50 [5]. In Vietnam, there have been no a national statistics on Graves’ disease. According to Le Huy Lieu, Graves disease accounted for 45.8% of patients with endocrine disease and 2.6% of internal diseases in Bachmai Hospital. Currently, there were 3 treatment options for Graves’ patient: internal treatment, radioactive iodine therapy and surgery. Each method had its own strengths and weaknesses, which needs appropriate indication. Open surgery for Graves’ disease has been strongly developed since the 1990s and has achieved extremely high results: 95 - 97% curable, the low incidence of accidents .
