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Objectives: Sphenoid wing meningiomas (SWMs) are skull base tumors that are associated with significant morbidity and mortality, especially in medial sphenoid wing meningiomas (MSWMs) as their anatomic proximity to many critical neurological and vascular structures. This study aimed to evaluate the clinical outcome and SWM surgical resection. | Journal of military pharmaco-medicine no3-2018 SPHENOID WING MENINGIOMA: MICROSURGERY AND CLINICAL OUTCOMES IN VIETDUC HOSPITAL Do Van Dung*; Dong Van He**; Vu Van Hoe*** SUMMARY Objectives: Sphenoid wing meningiomas (SWMs) are skull base tumors that are associated with significant morbidity and mortality, especially in medial sphenoid wing meningiomas (MSWMs) as their anatomic proximity to many critical neurological and vascular structures. This study aimed to evaluate the clinical outcome and SWM surgical resection. Subjects and methods: A descriptive and interventional study was conducted on 60 SWMs which were operated from 2013 to 2015 at Vietduc Hospital. Result and conclusion: According to Simpson’s classification, tumor resection grade I and II accounted for 60%, good outcome (KPS 80-100) achieved in 65% of the patients, average outcome: 35%, mortality 5%. Visual improved in 23.81%. Cranial nervous outcome: III 65.39%, V: 29.2%, IV: 57.14%, VI: 53.85%. Recurrence 15.4%, follow-up period 14.5 months. * Keywords: Sphenoid wing meningiomas; Microsurgery; Clinical outcome. INTRODUCTION Sphenoid wing meningiomas (SWMs) are in the skull base tumors, accounting for approximately 15 - 20% of intracranial meningiomas. It was divided into three groups on the basis of preoperative radiology findings: lateral, middle, medial. Among them, there are some parts related to the medial, such as internal carotid, cavernous sinus and cranial nervous II, III, IV, V, VI. As a result, how to resect the whole tumor but still preserve the relevant components to improve the cranial nervous outcome and the quality of life after operation is an emerging issue that neurosurgeons are faced with. However, the results vary from center to center due to many factors. Some recent reports also inform that the rate of total tumors resection ranges from 59 to 86.7%, mortality remains as high as 14.5%, cranial neuro increases from 4 to 29%. SUBJECTS AND METHODS 1. Subjects. 60 patients were .
