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(BQ) Part 2 book “The ADA practical guide to soft tissue oral disease” has contents: Differential diagnosis of common oral soft tissue lesions, guidelines for observation and/or referral of patients’ lesions, the art and science of biopsy and cytology, sample patient histories and discussion. | 4 Differential Diagnosis of Common Oral Soft Tissue Lesions Following the initial comprehensive head and neck soft tissue examination (Chapter 1), the clinician can identify the lesion as arising in the soft tissue and provide its detailed description (Chapter 2), determine its appropriate category (e.g. white lesion that rubs off, red lesion, and ulceration) as listed in Chapter 3, and then create a nonprioritized list of all possible soft tissue lesions that may produce a similar clinical picture. The next step is to create a prioritized differential diagnosis list; the list should be rearranged with the most probable lesion ranked at the top and the least likely at the bottom. The process of priority ranking can be complicated at times, so it behooves the clinician to be familiar with the signs and symptoms produced by a great many diseases and to possess statistical knowledge relative to the incidence of each disease entity. The priority ranking is directly related to the relative incidence of the lesions if all other factors about the lesions are similar. Thus, in developing a clinical differential diagnosis, the clinician first ranks the lesions in order of their relative frequency of occurrence and then modifies this order based on age, gender, race, and anatomic location. A special case can exist in which two or more lesions are synchronously present. If so, then seven possibilities must be considered: • Lesions A and B are completely unrelated: 1. Lesions A and B are both present as a matter of chance. • Lesions A and B are related: 2. Lesion A and Lesion B are identical. 3. Lesion B is secondary to Lesion A. 4. Lesion A is secondary to Lesion B. The ADA Practical Guide to Soft Tissue Oral Disease, Second Edition. Michael A. Kahn and J. Michael Hall. © 2018 by the American Dental Association. Published 2018 by John Wiley & Sons, Inc. 115 116 Diagnosis and Management 5. Lesion A and Lesion B are both secondary to a third lesion, which may .
