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Ebook The NeuroProcessor has contents: Introduction, recording from biological neural networks, the neuroprocessor, integrated front end for neuronal recording, algorithms for neuroprocessor spike sorting, MEA on Chip,.and other contenst. | The NeuroProcessor Yevgeny Perelman · Ran Ginosar The NeuroProcessor An Integrated Interface to Biological Neural Networks 13 Dr. Yevgeny Perelman Technion-Israel Institute of Technology Dept. Electrical Engineering 32 000 Haifa Israel perelman@tx.technion.ac.il ISBN: 978-1-4020-8725-7 Prof. Ran Ginosar Technion - Israel Institute of Technology Dept. Electrical Engineering 32000 Haifa Israel ran@ee.technion.ac.il e-ISBN: 978-1-4020-8726-4 Library of Congress Control Number: 2008932564 c 2008 Springer Science+Business Media B.V. No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Printed on acid-free paper 9 8 7 6 5 4 3 2 1 springer.com Contents 1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1.1 Overview of the Book . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 3 2 Recording From Biological Neural Networks . . . . . . . . . . . . . . . 2.1 The Neuron . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.1.1 The Membrane and Resting Potential . . . . . . . . . . . . . . . . 2.1.2 Action Potential . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.1.3 Excitation Propagation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.2 Interfacing Neurons Electrically . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.2.1 Double Layer Capacitance . . . . . . . . . . . . . . . . . . . . . . . . . . 2.2.2 Resistance at the Interface and Charge Transfer . . . . . . . 2.2.3 Diffusion Resistance Near DC . . . . . . . . . . . . . . . . . . . . . . . 2.2.4 AC .