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A clinical retrospective study of prognostic factors in tetanus patients (2016-2017)

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Objectives: To determine various prognostic factors in tetanus patients during the period 2016 - 2017. Subjects: 64 patients were diagnosed tetanus, ages over 17, treated in the Department of Infectious Diseases at 103 Hospital and National Hospital of Tropical Diseases from June, 2016 to April, 2017. | Journal of military parmaco-medicine n07-2017 A CLINICAL RETROSPECTIVE STUDY OF PROGNOSTIC FACTORS IN TETANUS PATIENTS (2016 - 2017) Hoang Vu Hung*; Nguyen Lan Phuong*; Dinh Thi Phuong Lien* Han Minh Thuy**; Hoang Thi Thanh**; Luu Thi Nhan** SUMMARY Objectives: To determine various prognostic factors in tetanus patients during the period 2016 - 2017. Subjects: 64 patients were diagnosed tetanus, ages over 17, treated in the Department of Infectious Diseases at 103 Hospital and National Hospital of Tropical Diseases from June, 2016 to April, 2017. Method: The cross-sectional retrospective, descriptive study. Results: A total of the 64 patients with diagnosis of tetanus, had 53 male (70.31%) and 15 female (29.69%). The mean age was 58.7 ± 15.7 years (range 18 - 94). The outcomes of treatment were divided into two groups: 7 patients with dead, severe disease and 57 survivors. There was a significant difference between two groups in patients with dead and more severe disease and cured patients observed in relation to more severe prognostic factors were the incubation period 17 years with diagnosis of tetanus, who admitted to the Department of Infectious Diseases of 103 Hospital and National Hospital of Tropical Diseases between June, 2016 and April, 2017 enrolled in this crosssectional descriptive study. The study protocol was reviewed and approved by the institutional review board of 103 Hospital and National Hospital of Tropical Diseases. * Inclusion criteria [1]: - Patients had suspicious wound with the point of entry. - Clinical symptoms at onset of the first trismus, then skeletal muscles spasm of the head, neck, and trunk. - Patients had percusive seizure with increased muscular tone. Data were analyzed and compared between patients in group 1 and group 2 using SPSS 13.0. Chi-square test used for categorical variables or Fisher’s exact tests as appropriate and student’s t-tests and Mann - Whitney U test for quantitative variables. Logistic regression was used

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