TAILIEUCHUNG - Evaluate dose distribution of IMRT and VMAT technique in radiotherapy for head and neck cancer using truebeam STx linear accelerator

Objectives: To evaluate and compare dose distribution between IMRT and VMAT plan in radiotherapy for head and neck cancer using TrueBeam STx accelerator. Subjects and methods: CT imaging of head and neck cancer’s patients treated with VMAT on the TrueBeam STx accelerator was used to replan using IMRT technique in TPS Eclipse . | Journal of military pharmaco-medicine no1-2019 EVALUATE DOSE DISTRIBUTION OF IMRT AND VMAT TECHNIQUE IN RADIOTHERAPY FOR HEAD AND NECK CANCER USING TRUEBEAM STX LINEAR ACCELERATOR Pham Hong Lam1; Nguyen Thi Van Anh2; Pham Quang Trung2 SUMMARY Objectives: To evaluate and compare dose distribution between IMRT and VMAT plan in radiotherapy for head and neck cancer using TrueBeam STx accelerator. Subjects and methods: CT imaging of head and neck cancer’s patients treated with VMAT on the TrueBeam STx accelerator was used to replan using IMRT technique in TPS Eclipse . Conformity index, gradient index and homogeneity index were used to compare plan quality and dose distribution at planning target volume, organs at risk. Results: The dose distribution on planning target volume of IMRT technique based on CI100 - Paddick, HIRTOG index ( ± , ± ) gave the same value as the VMAT technique ( ± 0, 44, ± ). Maximum doses on organs at risk such as spinal cord, brainstem, and mandible received from IMRT technique were a little lower than the doses from VMAT technique. Conclusion: The IMRT technique is equivalent to the VMAT based on coverage, ability to focus dose on the planning target volume and the ability to spare dose to critical organs. Both the IMRT and VMAT technique on the TrueBeam STx Linac can be selected to treat head and neck cancer patients in 108 Military Central Hospital. * Keywords: Head and neck cancer; IMRT; VMAT; Conformity index; Homogeneity index; Gradient index. INTRODUCTION Radiation therapy is one of the main modalities for cancer treatment. The linear accelerator (Linac) is an indispensable device and it is the most basic component of an external radiotherapy. Especially, radiation therapy plays an important role in head and neck cancer treatment. The biggest difficulty with the treatment of head and neck cancer by radiotherapy is that it has a large number of critical organs near treatment volume. Organs at risk

• Y khoa - Dược
• Head and neck cancer
• Conformity index
• Homogeneity index
• Gradient index
• Planning target volume
• Organs at risk
• BMC Cancer
• Head and neck squamous cell carcinoma
• Immune checkpoint inhibitors
• Survival in head and neck cancer
• Alcohol consumption
• Cigarette smoking
• Cohort studies
• Head neck cancer
• Head neck cancer subtypes
• Progressive resistance training
• Physical activity
• Body composition
• Clinical cohort
• Prognosis research
• Patient reported outcomes
• Sexual history
• Quality of life
• Biological samples
• Cell Line Microarray
• Potential immunohistochemical biomarkers
• Triple treatment combination
• Immunotherapy targeting
• Metastatic head
• Neck squamous cell carcinoma
• Cancer stem cells
• Side population
• Delayed neck metastasis
• Inflammatory marker
• Systemic inflammation
• Nonstandard treatment
• Patient compliance
• Cumulative incidence
• Esophageal cancer
• Metachronous cancer
• Young onset
• Head and neck
• Phase III
• Squamous cell carcinoma
• Overall survival
• Platinum therapy
• Narrow band imaging
• Second primary cancer
• Radiation dermatitis
• Topical steroid
• Neck cancer
• Patient derived xenograft
• Squamous cell cancer
• Anti cancer therapeutics
• Warburg effect
• Alternative splicing
• Pyruvate Kinase muscle isoenzyme
• Cancer cells
• Single nucleotide polymorphism
• Personalized medicine
• 5 lipoxygenase
• Representative endocannabinoids
• Effectively inhibited
• Treatment outcome
• Induction chemotherapy
• Neck squamous cells carcinomas
• Metabolic statuses
• CUP syndrome
• Delayed adjuvant therapy
• Advanced head and neck cancer
• Neck dissection
• Human papillomavirus
• Oropharyngeal cancer
• Laryngeal cancer
• Oral cancer
• Chemo radiotherapy exhibiting weak
• Locoregional cancer
• Aspiration pneumonia
• Risk factors
• Cancer related mortality
• Tumor growth
• Meta analysis
• Cancer worldwide
• Anti CD44 v6 antibody
• Antineoplastic treatment
• Indicating greater difficulties
• Circulating tumor cell
• Circulating tumor DNA
• Oral cavity cancer preclinical model