TAILIEUCHUNG - Lecture Molecular biology (Fifth Edition): Chapter 23 - Robert F. Weaver

Chapter 23 introduce to transposition. This chapter presents the following content: Bacterial transposons, Eukaryotic transposons, rearrangement of immunoglobulin genes, retrotransposons. | Molecular Biology Fifth Edition Chapter 23 Transposition Lecture PowerPoint to accompany Robert F. Weaver Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Bacterial Transposons A transposable element moves from one DNA address to another Originally discovered in maize, transposons have been found in all kinds of organisms Bacteria Plants Humans 23- Discovery of Bacterial Transposons Phage coat is made of protein Always has the same volume DNA is much denser than protein More DNA in phage, denser phage Extra DNAs that can inactivate a gene by inserting into the gene were the first transposons discovered in bacteria These transposons are called insertion sequences (ISs) 23- Insertion Sequences Insertion sequences are the simplest type of bacterial transposon They contain only the elements necessary for their own transposition Short inverted repeats at their ends At least 2 genes coding for an enzyme, transposase that carries out .

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• Bacterial transposons
• Eukaryotic transposons
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