TAILIEUCHUNG - Lecture Molecular biology: Chapter 14 - Robert F. Weaver

Chapter 14 - Messenger RNA processing I: Splicing. In this chapter we will see that most eukaryotic genes, in contrast to typical bacterial genes, are interrupted by noncoding DNA. RNA polymerase cannot distinguish the coding region of the gene from the noncoding regions, so it transcribes everything. | Molecular Biology Fourth Edition Chapter 14 Messenger RNA Processing I: Splicing Lecture PowerPoint to accompany Robert F. Weaver Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Genes in Pieces Consider the sequence of the human b-globin gene as a sentence: This is bhgty the human b-globin qwtzptlrbn gene. Two italicized regions make no sense Contain sequences unrelated to the globin coding sequences surrounding them Called intervening sequences, IVSs Usually called introns Parts of the gene making sense Coding regions Exons Some lower eukaryotic genes have no introns 14- Evidence for Split Genes Most higher eukaryotic genes coding for mRNA and tRNA are interrupted by unrelated regions called introns Other parts of the gene, surrounding the introns, are called exons Exons contain the sequences that finally appear in the mature RNA product Genes for mRNAs have been found with anywhere from 0 to 362 exons tRNA genes have either 0 or

• Sinh học
• Molecular biology
• Lecture Molecular biology
• Sinh học phân tử
• Amino acids
• Messenger RNA processing I
• Genes in pieces
• High Yield cell and molecular biology
• Cell and molecular biology
• The cell cycle
• Molecular biology of cancer
• Cell biology of the immune system
• Molecular biology techniques
• Identification of human disease genes
• Campbell biology
• Lecture Campbell biology
• Biological sciences
• Systems biology
• Molecular biology of the gene
• Chromosome replication
• Meiosis and genetic recombination
• The human nuclear genome
• The human mitochondrial genome
• Molecular cloning methods
• Gene cloning
• Directional cloning
• Molecular tools
• Studying genes
• History of genetics
• Both simple
• Molecular genetics
• Genetic code
• Molecular biology of microorganisms
• Different facets
• Plant molecular biology
• Genetic manipulation
• Recombinant DNA technology
• Molecular diagnostics
• Biochemistry cell and molecular biology test
• Molecular Biology Test
• Biochemistry Test
• Genetics test
• Structural Biology
• Cupramolecular complexes
• Lecture Biology
• Mendel’s Laws
• Transmission genetics
• Mendel’s gene transmission
• Genetic material
• Transforming material
• DNA structure
• Gene function
• Storing information
• Mechanism of transcription
• RNA polymerase structure
• Lac operon
• Bacterial transcription
• Sigma factor switching
• DNA Protein interactions
• The λ family of repressors
• Eukaryotic RNA polymerases
• RNA polymerases
• Class II factors
• Transcription activators in eukaryotes
• RNA polymerase II
• Histones in the nucleosome
• Nucleosome structure
• RNA processing II
• Cap structure
• Cytoplasmic polyadenylation
• RNA processing
• Ribosomal RNA processing
• Transfer RNA processing