TAILIEUCHUNG - WGO practice guideline: Management of strongyloidiasis

Document presentation of content: Introduction & key points, disease burden & endemicity, risk groups, diagnosis and differential diagnosis, management of strongyloidiasis, literature references, useful websites, queries and feedback from you. | WGO Practice Guideline Management of Strongyloidiasis 28 October 2004 Review Team Professor M. Farthing Chair - World Gastroenterology Organisation Professor S. Fedail World Gastroenterology Organisation Dr. L. Savioli World Health Organisation Dr. . Bundy World Bank . Krabshuis Highland Data Contents 1. Definition 2. Introduction Key Points 3. Disease Burden Endemicity 4. Risk Groups 5. Diagnosis and Differential Diagnosis 6. Management of Strongyloidiasis 7. Literature References 8. Useful Websites 9. Queries and Feedback from you 1. Definition Strongyloidiasis is an infection with Strongyloides stercoralis a round worm occurring widely in tropical and subtropical areas. The genus Strongyloides is classified in the order Rhabditida and most members are soildwelling microbiverous nematodes. Fifty-two species of Strongyloides exist but most do not infect humans. S. stercoralis is the most common pathogen for humans. The adult male worm is passed in the stool after fertilizing the female worm - it is not a tissue parasite. The adult female worm is very small and almost transparent. It measures approximately mm in length with a diameter of 50 pm it lives in tunnels between the enterocytes in the human small bowel. Strongyloides stercoralis is different from all other soil transmitted helminthic infections because the female worm can reproduce by parthogenesis within the human host. Depending on the host immune response this can lead to autoinfection and hyperinfection. Terminology autoinfection the process that enables the parasite to survive very long in the human host mostly asymptomatically. Hyper-infection the process of intense auto-infection the phase in which third stage larvae can be found in fresh stools. Disseminated infection the outcome of hyperinfection larvae can be found anywhere particularly in sputum and skin. Figure 1. Strongyloides stercoralis first stage larvae Strongyloides stercoralis first-stage larva L. preserved in 10 formalin.

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• Introduction & key points
• Management of strongyloidiasis
• WGO practice guideline
• Disease burden & endemicity
• Diagnosis and differential diagnosis
• Management of strongyloidiasis
• Literature references
• Climate change
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• Document Dysphagia
• Introduction and key points
• Disease burden and epidemiology
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