TAILIEUCHUNG - Báo cáo y học: " Five-year mortality in a cohort of people with schizophrenia in Ethiopia"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Five-year mortality in a cohort of people with schizophrenia in Ethiopia | Teferra et al. BMC Psychiatry 2011 11 165 http 1471-244X 11 165 BMC Psychiatry RESEARCH ARTICLE Open Access Five-year mortality in a cohort of people with schizophrenia in Ethiopia 1 2 3 1 Solomon Teferra Teshome Shibre Abebaw Fekadu Girmay Medhin Asfaw Wakwoya Atalay Alem Gunnar Kullgren4 and Lars Jacobsson4 Abstract Background Schizophrenia is associated with a two to three fold excess mortality. Both natural and unnatural causes were reported. However there is dearth of evidence from low and middle income LAMIC countries particularly in Africa. To our knowledge this is the first community based report from Africa. Methods We followed a cohort of 307 males patients with schizophrenia for five years in Butajira rural Ethiopia. Mortality was recorded using broad rating schedule as well as verbal autopsy. Standardized Mortality Ratio SMR was calculated using the mortality in the demographic and surveillance site as a reference. Result Thirty eight patients 34 men and 4 women died during the five-year follow up period. The mean age SD of the deceased for both sexes was 35 . The difference was not statistically significant p . It was for men and for women. The most common cause of death was infection 18 38 followed by severe malnutrition 5 38 and suicide 4 38 . The overall SMR was 95 CI . Rural residents had lower mortality with adjusted hazard ratio HR of 95 CI but insidious onset and antipsychotic treatment for less than 50 of the follow up period were associated with higher mortality adjusted HR 95 CI and respectively. Conclusion The alarmingly high mortality observed in this patient population is of major concern. Most patients died from potentially treatable conditions. Improving medical and psychiatric care as well as provision of basic needs is recommended. Background Schizophrenia is often called a life .

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