TAILIEUCHUNG - ANAESTHETIC MANAGEMENT OF SICKLE CELL DISEASE IN CHILDREN ANAESTHESIA TUTORIAL OF THE WEEK 153


The conditions in which women and children are born, grow up, live and work have a major impact on their health. Efforts to improve health must be closely linked to those intended to tackle poverty and malnutrition, improve access to education, ensure gender equity and empowerment, tackle major diseases, and improve access to safe drinking water, adequate sanitation and a clean, safe environment. Integrating the care of women and children with other services is an efficient and cost-effective route to success. For example, investing in family planning in addition to maternal and newborn services can save US$ billion while achieving. | Sign up to receive ATOTW weekly - email worldanaesthesia@ ANAESTHETIC MANAGEMENT OF SICKLE CELL DISEASE IN CHILDREN ANAESTHESIA TUTORIAL OF THE WEEK 153 28th SEPTEMBER 2009 Christie Locke SpR Anaesthesia Great Ormond Street Hospital NHS UK Correspondence to christielocke@ SELF-ASSESSMENT QUESTIONS Before continuing try to answer the following questions. Choose the single best answer. The answers can be found at the end of the article. 1. Normal adult red blood cells contain a. HbA HbAS HbF HbS b. HbA HbA2 HbF c. HbA HbF HbS d. HbA1 HbA2 HbF e. HbA HbAS HbFS HbF 2. Sickle cell disease is most commonly found in which populations a. Southern Africa b. India and Asia c. Caribbean and West Africa d. North America e. Southern Europe 3. What is the most common site for a painful crisis in a patient with sickle cell disease a. Head and neck b. Abdomen c. Bones and joints d. Chest e. Kidneys 4. Which statement best describes the typical clinical presentation of acute chest syndrome in a patient with sickle cell disease a. Chest pain and shortness of breath without a fever b. Hypoxia with no other clinical signs c. Shortness of breathe and wheeze d. Fever and bilateral infiltrates on CXR e. Fever chest pain and lobar infiltrate on CXR 5. Which test is the gold standard for diagnosis of sickle cell disease a. Haemoglobin electrophoresis b. Gas chromatography c. DNA analysis d. Sickle solubility test e. Peripheral blood film ATOTW 153 - Sickle Cell Disease in Childhood 28 09 2009 Page 1 of 8 Sign up to receive ATOTW weekly - email worldanaesthesia@ 6. What are the main principles of the perioperative management of a patient with sickle cell disease a. Oxygenation hydration analgesia avoidance of acidosis routine preoperative blood transfusion b. Oxygenation hyperhydration analgesia maintenance of normothermia avoidance of acidosis c. Oxygenation hydration analgesia maintenance of normothermia avoidance of acidosis d. Oxygenation hyperhydration analgesia .

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