TAILIEUCHUNG - Báo cáo khoa học: "Upregulated but insufficient generation of activated protein C is associated with development of multiorgan failure in severe acute pancreatitis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Upregulated but insufficient generation of activated protein C is associated with development of multiorgan failure in severe acute pancreatitis. | Available online http content 10 1 R16 Research Upregulated but insufficient generation of activated protein C is associated with development of multiorgan failure in severe acute pancreatitis Outi Lindstrom1 Leena Kylanpaa1 Panu Mentula1 Pauli Puolakkainen1 Esko Kemppainen1 Reijo Haapiainen1 Jose A Fernandez2 John H Griffin2 Heikki Repo3 4 and Jari Petaja5 Second Department of Surgery Helsinki University Central Hospital and University of Helsinki Finland 2Department of Molecular and Experimental Medicine The Scripps Research Institute La Jolla CA USA 3Department of Medicine University of Helsinki Finland 4Department to Bacteriology and Immunology Haartman Institute University of Helsinki Finland 5Department of Pediatrics Jorvi Hospital Espoo Finland Corresponding author Leena Kylanpaa Received 19 Aug 2005 Revisions requested 26 Sep 2005 Revisions received 15 Oct 2005 Accepted 12 Dec 2005 Published 13 Jan 2006 Critical Care 2006 10 R16 doi cc3966 This article is online at http content 10 1 R1 6 2006 Lindstrom et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Disturbed protein C PC pathway homeostasis might contribute to the development of multiple organ failure MOF in acute pancreatitis AP . We therefore evaluated circulating levels of PC and activated protein C APC evaluated monocyte deactivation in AP patients and determined the relationship of these parameters to MOF. Patients and methods Thirty-one patients in the intensive care unit were categorized as cases n 13 severe AP with MOF or controls n 18 severe AP without MOF . Blood samples were drawn every second day to determine the platelet count the levels of APC PC and D-dimer

TỪ KHÓA LIÊN QUAN
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.