TAILIEUCHUNG - On public health use of influenza antivirals during influenza pandemics (with particular reference to the pandemic (H1N1) 2009)

The retirement crisis will have significant repercussions. As older Americans transition out of the workforce, either voluntarily or involuntarily, many will find that they cannot afford basic living expenses. They will be forced to make the difficult choice between putting food on the table and buying their medication. The retirement crisis will put an enormous strain on our families, our communities, and our social safety net. | ECDC HEALTH EDUCATION On public health use of influenza antivirals during influenza pandemics with particular reference to the pandemic H1N1 2009 Introduction This document is a summary of an ECDC Interim Guidance called public health use of influenza antivirals during influenza pandemics . The guidance is based on scientific evidence expert opinions and recommendations included in various national pandemic preparedness plans in EU countries. It aims at serving as a resource document for those in Europe developing policies on the use of antivirals in an influenza pandemic It draws on the following document available on the ECDC website http en publications Publications 0907 GUIPublicHealthuseofInfluenzaAntiviralsdu ringInfluenza What are antivirals Antivirals are a group of medicines intended for treating or to a lesser extent preventing viral infections affecting humans. They are a relatively new but important addition to the list of countermeasures against influenza. Antivirals are considered especially important for older people those with chronic illnesses and others with weakened immunity. Currently there are two main classes of antivirals used for influenza treatment and prophylaxis The more recent Neuraminidase Inhibitors NIs oseltamivir and zanamivir and M2-Inhibitors or Adamantanes amantidine and rimantidine . These drugs are not relevant for the pandemic H1N1 2009 because all of the viruses tested to date have been resistant to this class of antiviral. A few other drugs are reported to be in development but are not yet available. There has been great interest in the potential use of antivirals during influenza pandemics because when a pandemic occurs most humans will lack immunity and it will take several months to develop and license specific vaccines. Also if vaccine supply is not sufficient initially antivirals could fill the vaccine gap providing clinicians and public health specialists with a tool that can be used to .

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