TAILIEUCHUNG - Faculty of Sexual & Reproductive Healthcare Clinical Guidance

in 1991 the North-West region declared the independent state of Somaliland, which has not been recognised as independent by the majority of other countries. Nevertheless, Somaliland enjoys relative peace and security and is de facto administered from its capital, Hargeisa. in 1998 the North-east declared itself as the autonomous region of Puntland. Puntland has not sought separate statehood but declared its intention to participate in any Somali reconciliation and reconstruction process. Since 1998 Puntland has also been de facto governed by its own administration based in its capital, garowe. the South central Zone of Somalia remains locked in intermittent political conflict and. | -------FACULTY-------- -----OF SEXUAL------ REPRODUCTIVE HEALTHCARE Faculty of Sexual Reproductive Healthcare Clinical Guidance Drug Interactions with Hormonal Contraception Clinical Effectiveness Unit January 2011 Updated January 2012 ISSN 1755-103X DETAILS OF CHANGES TO ORIGINAL GUIDANCE DOCUMENT Page 9 of the original version of this CEU Guidance Document issued in January 2011 incorrectly stated that the interaction between lamotrigine and combined hormonal contraception CHC only applies to lamotrigine monotherapy. CHC also reduces lamotrigine levels when lamotrigine is combined with antiepileptic drugs that do not alter its metabolism. ABBREVIATIONS USED BNF British National Formulary CEU Clinical Effectiveness Unit CHC combined hormonal contraception COC combined oral contraceptive Cu-IUD copper-bearing intrauterine device DMPA depot medroxyprogesterone acetate EC emergency contraception EE ethinylestradiol FSRH Faculty of Sexual and Reproductive Healthcare HIV human immunodeficiency virus LNG levonorgestrel LNG-IUS levonorgestrel-releasing intrauterine system NET-EN norethisterone enantate PEPSE post-exposure prophylaxis after sexual exposure to HIV POP progestogen-only pill SPC Summary of Product Characteristics UKMEC UK Medical Eligibility for Contraceptive Use UPA ulipristal acetate UPSI unprotected sexual intercourse USMEC . Medical Eligibility Criteria for Contraceptive Use WHOMEC World Health Organization Medical Eligibility for Contraceptive Use GRADING OF RECOMMENDATIONS Evidence based on randomised controlled trials Evidence based on other robust experimental or observational studies Evidence is limited but the advice relies on expert opinion and has the endorsement of respected authorities Good Practice Point where no evidence exists but where best practice is based on the clinical experience of the multidisciplinary group Published by the Faculty of Sexual and Reproductive Healthcare Registered in England No. 2804213 and Registered Charity No.

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