TAILIEUCHUNG - Báo cáo khoa học: " 4D treatment planning for scanned ion beams"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " 4D treatment planning for scanned ion beams. | Radiation Oncology BioMed Central Research 4D treatment planning for scanned ion beams Christoph Bert and Eike Rietzel Open Access Address Gesellschaft fur Schwerionenforschung GSI Abteilung Biophysik Planckstrafie 1 64291 Darmstadt Germany Email Christoph Bert - Eike Rietzel - eike@ Corresponding author Published 3 July 2007 Received 5 April 2007 Radiation Oncology 2007 2 24 doi 1748-717X-2-24 Accepted 3 July 2007 This article is available from http content 2 1 24 2007 Bert and Rietzel licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract At Gesellschaft fur Schwerionenforschung GSI more than 330 patients have been treated with scanned carbon ion beams in a pilot project. To date only stationary tumors have been treated. In the presence of motion scanned ion beam therapy is not yet possible because of interplay effects between scanned beam and target motion which can cause severe mis-dosage. We have started a project to treat tumors that are subject to respiratory motion. A prototype beam application system for target tracking with the scanned pencil beam has been developed and commissioned. To facilitate treatment planning for tumors that are subject to organ motion we have extended our standard treatment planning system TRiP to full 4D functionality. The 4D version of TRiP allows to calculate dose distributions in the presence of motion. Furthermore for motion mitigation techniques tracking gating rescanning and internal margins optimization of treatment parameters has been implemented. 4D calculations are based on 4D computed tomography data deformable registration maps organ motion traces and beam scanning parameters. We describe the methods of our 4D treatment .

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