TAILIEUCHUNG - Báo cáo khoa học: " Range accuracy in carbon ion treatment planning based on CT-calibration with real tissue samples"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Range accuracy in carbon ion treatment planning based on CT-calibration with real tissue samples | Radiation Oncology BioMed Central Open Access Range accuracy in carbon ion treatment planning based on CT-calibration with real tissue samples Eike Rietzel Dieter Schardt and Thomas Haberer Address Abteilung Biophysik Gesellschaft fur Schwerionenforschung Planckstr. 1 64291 Darmstadt Germany. Email Eike Rietzel - eike@ Dieter Schardt - Thomas Haberer - Corresponding author Published 23 March 2007 Received 31 October 2006 Accepted 23 March 2007 Radiation Oncology 2007 2 14 doi l748-7l 7X-2-I4 This article is available from http content 2 l l4 2007 Rietzel et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The precision in carbon ion radiotherapy depends on the calibration of Hounsfield units HU as measured with computed tomography CT to water equivalence. This calibration can cause relevant differences between treatment planning and treatment delivery. Methods Calibration data for several soft tissues were measured repeatedly to assess the accuracy of range calibration. Samples of fresh animal tissues including fat brain kidney liver and several muscle tissues were used. First samples were CT scanned. Then carbon ion radiographic measurements were performed at several positions. Residual ranges behind the samples were compared to ranges in water. Results Based on the measured data the accuracy of the current Hounsfield look-up table for range calibration of soft tissues is . Accuracy in range calibration of l corresponds to l mm carbon ion range control in l0 cm water equivalent depth which is comparable to typical treatment depths for head and neck tumors. Conclusion Carbon ion ranges can be controlled within l mm in soft

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