TAILIEUCHUNG - Báo cáo y học: " Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays. | Available online http content 8 4 R1 22 Research article Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays Bert Vander Cruyssen1 Tineke Cantaert1 Leonor Nogueira2 Cyril Clavel2 Leen De Rycke1 Amélie Dendoven1 Mireille Sebag2 Dieter Deforce3 Christian Vincent2 Dirk Elewaut1 Guy Serre2 and Filip De Keyser1 Department of Rheumatology Ghent University Hospital Ghent Belgium 2UMR 5165 Laboratory of Epidermis Differentiation and Rheumatoid Autoimmunity CNRS - Toulouse III University Toulouse France laboratory of Pharmaceutical Biotechnology Ghent University Ghent Belgium Contributed equally Corresponding author Bert Vander Cruyssen Received 28 Mar 2006 Revisions requested 1 Jun 2006 Revisions received 6 Jul 2006 Accepted 13 Jul 2006 Published 19 Jul 2006 Arthritis Research Therapy 2006 8 R122 doi ar2011 This article is online at http content 8 4 R122 2006 Vander Cruyssen et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract We studied the diagnostic performance of the anti-human citrullinated fibrinogen antibody AhFibA ELISA for rheumatoid arthritis RA in a consecutive cohort population 1 and evaluated the agreement between the AhFibA ELISA and four other assays for anti-citrullinated protein peptide antibodies ACPAs as well as rheumatoid factor in patients with longstanding RA population 2 . Population 1 consisted of 1024 patients with rheumatic symptoms serum samples from these patients were sent to our laboratory for ACPA testing within the context of a diagnostic investigation for RA. Ninety-two of these patients were classified as having RA .

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