TAILIEUCHUNG - Báo cáo khoa học: "Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas | BioMed Central World Journal of Surgical Oncology Research Expression of the metalloproteases MMP-1 MMP-2 MMP-3 MMP-9 MMP-11 TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas Abelardo Meneses-Garcia1 Alejandro Mohar Betancourt1 Jorge Herrera Abarca2 Adriana Becerril Montes2 Lourdes Suarez Roa1 and Luz Ruíz-Godoy 3 Address 1Pathology department Institute Nacional de Cancerología México 2Pharmacology department Institute Politécnico Nacional México and 3Basic research Instituto Nacional de Cancerologia México Email Abelardo Meneses-Garcia - aameneses@ Alejandro Mohar Betancourt - moharalejandro@ Jorge Herrera Abarca - macinves@ Adriana Becerril Montes - abmontes@ Lourdes Suarez Roa - lusuroa@ Luz Ruiz-Godoy - lruizgodoy@ Corresponding author Open Access Published 27 October 2008 Received 23 April 2008 World Journal of Surgical Oncology 2008 6 114 doi 1477-7819-6-114 Accepted 27 October 2008 This article is available from http content 6 1 114 2008 Meneses-García et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Extranodal T NK cell lymphomas possess distinctive clinico-pathological characteristics they are angiocentric exhibit extensive necrosis. Prognosis is poor in the short term. The objective is to explore the expression of different MMPs in the cells and stroma which are around of the blood vessels damaged and their correlation with clinico-pathological parameters. Patients and methods Twenty cases of this type of lymphomas were studied and collected patient clinical data. The expressions of MMP-1 2 3 9 11 13 and TIMP-1 2 were studied .

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