TAILIEUCHUNG - Báo cáo khoa học: "Small cell carcinoma in ulcerative colitis - new treatment option: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Small cell carcinoma in ulcerative colitis - new treatment option: a case report | Kosmidis et al. World Journal of Surgical Oncology 2010 8 100 http content 8 1 100 WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Small cell carcinoma in ulcerative colitis -new treatment option a case report Christoforos Kosmidis Christoforos Efthimiadis Georgios Anthimidis Kalliopi Vasiliadou Ioanna Tzeveleki Panagiotis Fotiadis Georgios Basdanis Abstract Background The most common type of carcinoma associated with ulcerative colitis UC is adenocarcinoma. We present a case of primary rectal small cell carcinoma in a patient with a history of UC. Methods A 34-year-old male diagnosed with UC for 10 years was not consistent with the usual annual follow-up and presented with mucoid-bloody diarrhea. Colonoscopy revealed a rectal mass 2 cm distant from the anal verge. The patient underwent a total proctocolectomy with preservation of the anal sphincters construction of an ileal reservoir anastomosis of the reservoir to the anus J configuration and protective loop ileostomy. Results Histological examination showed undifferentiated small cell carcinoma. Conclusions This is the first case of small cell carcinoma in a background of UC reported to be treated surgically and the patient and has no reccurence 18 months postoperatively. Background Primary small cell carcinoma SCC of the colon and the rectum is very rare with an incidence of less than 0 2 of all colorectal cancers 1 . The most common histological type of carcinoma associated with ulcerative colitis is adenocarcinoma 2 . We present a case of primary rectal small cell carcinoma in a patient with a history of ulcerative colitis which is the fifth case reported and the first treated surgically. Methods Case presentation A 34-year-old male diagnosed with ulcerative colitis for 10 years presented with mucoid-bloody diarrhea and none extraintestinal manifestation. His haemoglobin was 10 6 gr dl. The patient had been prescribed methylprednisolone 24 gr daily during the last years but he was not

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