TAILIEUCHUNG - GENE THERAPY DEVELOPMENTS AND FUTURE PERSPECTIVES

In the first section of this book, ‘Retroviral Vector’, chapter one discusses the efficiency of retroviral DNA integration, the preferences of integration for certain regions, and advances on integration site selection and gene therapy. Chapter two reviews and discusses the current cell lines and bioreaction platforms used for production of retroviral and lentiviral vectors, focusing on the current bottlenecks and future directions with a particular emphasis in the metabolic constrains. | GENE THERAPY -DEVELOPMENTS AND FUTURE PERSPECTIVES Edited by Chunsheng Kang Gene Therapy - Developments and Future Perspectives Edited by Chunsheng Kang Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access articles distributed under the Creative Commons Non Commercial Share Alike Attribution license which permits to copy distribute transmit and adapt the work in any medium so long as the original work is properly cited. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published articles. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Romina Krebel Technical Editor Teodora Smiljanic Cover Designer Jan Hyrat Image Copyright Anteromite 2010. Used under license from First published July 2011 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Gene Therapy - Developments and Future Perspectives Edited by Chunsheng Kang p. cm. ISBN 978-953-307-617-1 ikrrr iJ OPEN ACCESS INI Cvn PUBLISHER INTECH open free online editions of InTech Books and Journals can be found at .

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