TAILIEUCHUNG - Journal of Orthopaedic Surgery and ResearchResearch articleBioMed CentralOpen AccessIn vitro
Journal of Orthopaedic Surgery and Research Research article BioMed Central Open Access In vitro suppression of the MMP-3 gene in normal and cytokine-treated human chondrosarcoma using small interfering RNA Korakot Nganvongpanit*1, Patama Chaochird2, Puntita Siengdee2, Peraphan Pothacharoen3, Kasisin Klunklin4, Siriwadee Chomdej2, Supamit Mekchay5 and Prachya Kongtaweelert3 Address: 1Bone and Joint Research Laboratory, Department of Veterinary Biosciences and Public Health, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand, 2Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand, 3Thailand Excellence Centre for Tissue Engineering, Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand, 4Department of Orthopedics, Faculty. | Journal of Orthopaedic Surgery and Research BioMed Central Open Access In vitro suppression of the MMP-3 gene in normal and cytokine-treated human chondrosarcoma using small interfering RNA Korakot Nganvongpanit 1 Patama Chaochird2 Puntita Siengdee2 Peraphan Pothacharoen3 Kasisin Klunklin4 Siriwadee Chomdej2 Supamit Mekchay5 and Prachya Kongtaweelert3 Address 1Bone and Joint Research Laboratory Department of Veterinary Biosciences and Public Health Faculty of Veterinary Medicine Chiang Mai University Chiang Mai 50100 Thailand 2Department of Biology Faculty of Science Chiang Mai University Chiang Mai 50200 Thailand Thailand Excellence Centre for Tissue Engineering Department of Biochemistry Faculty of Medicine Chiang Mai University Chiang Mai 50200 Thailand 4Department of Orthopedics Faculty of Medicine Chiang Mai University Chiang Mai 50200 Thailand and 5Department of Animal Science Faculty of Agriculture Chiang Mai University Chiang Mai 50200 Thailand Email Korakot Nganvongpanit - korakot@ Patama Chaochird - rfunfun@ Puntita Siengdee - atatee_naka@ Peraphan Pothacharoen - Kasisin Klunklin - dr_gain@ Siriwadee Chomdej- siriwadee@ Supamit Mekchay - agismkch@ Prachya Kongtaweelert - pkongtaw@ Corresponding author Published 24 December 2009 Received 12 June 2009 Journal of Orthopaedic Surgery and Research 2009 4 45 doi l749-799X-4-45 Accepted 24 December 2009 This article is available from http content 4 1 45 2009 Nganvongpanit et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Matrix metalloproteinase MMPs synthesized and secreted from connective tissue .
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