TAILIEUCHUNG - Seminars in Nuclear Medicine VOL XXIX, NO 4

O UR GUEST editors have assumed the additional role of guest authors for this issue on the topic of Cardiovascular Nuclear Medicine. They have performed equally well, clearly defining the role of pharmacological stress testing in the assessment of cardiovascular disease. This alternative to standard treadmill exercise is achieving increased application with the availability of several agents that have significantly different pharmacological actions. | Seminars in Nuclear Medicine VOL XXIX NO 4 OCTOBER 1999 Letter From the Editors OUR GUEST editors have assumed the additional role of guest authors for this issue on the topic of Cardiovascular Nuclear Medicine. They have performed equally well clearly defining the role of pharmacological stress testing in the assessment of cardiovascular disease. This alternative to standard treadmill exercise is achieving increased application with the availability of several agents that have significantly different pharmacological actions. As Drs. Wexler and Travin point out approximately 60 of patients with suspected cardiovascular disease are stressed pharmacologically at our institution. The remaining articles in this issue are equally informative. Dr. Berman has synthesized his prodigious contributions to the cardiovascular nuclear medicine literature and presents a cogent review of the role of cardiovascular nuclear medicine in clinical decision making. This article is essential for anyone who performs or uses these studies. The algorithms presented for cardiovascular nuclear medicine are well thought out and critical to our use of these tests. Cardiovascular nuclear medicine plays a powerful role in risk stratification diagnosis and therapy. Another area of concern to many nuclear medicine physicians is the increasing use of stress echocardiography as a potential substitute for thallium and sestamibi studies. Dr. Verani defines for us the advantages and limitations of stress echocardiography in evaluating myocardial perfusion. The introduction of hypoxia markers for myocardial imaging is discussed along with many other exciting developments. These agents as discussed by Dr. Sinusas have the potential to allow US to directly image myocardial tissue which is hypoxic. Thrombosis and atherosclerotic plaques are lifethreatening problems that have obvious implications in the pathogenesis of heart disease. Unfortunately therapy of thrombosis with anticoagulants also is not .

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