TAILIEUCHUNG - Policy Issues in the Development of Personalized Medicine in Oncology: Workshop Summary

Personalized cancer medicine is defined as medical care based on the particular biological characteristics of the disease process in individual patients. By using genomics and proteomics, individuals can be classified into subpopulations based on their susceptibility to a particular disease or response to a specific treatment. They may then be given preventive or therapeutic interventions that will be most effective given their particular characteristics. In oncology, personalized medicine has the potential to be especially influential in patient treatment because of the complexity and heterogeneity of each form of cancer. However, the current classifications of cancer are not as useful as they need to be for making treatment decisions; current cancer classification. | Policy Issues in the Development of Personalized Medicine in Oncology WORKSHOP SUMMARY INSTITUTE Of MEDICINE Policy Issues in the Development of Personalized Medicine in Oncology WORKSHOP SUMMARY Margie Patlak and Laura Levit Rapporteurs National Cancer Policy Forum Board on Health Care Services INSTITUTE OF MEDICINE OF THE NATIONAL ACADEMIES THE NATIONAL ACADEMIES PRESS Washington . THE NATIONAL ACADEMIES PRESS 500 Fifth Street . Washington DC 20001 NOTICE The project that is the subject of this report was approved by the Governing Board of the National Research Council whose members are drawn from the councils of the National Academy of Sciences the National Academy of Engineering and the Institute of Medicine. This study was supported by Contract Nos. HHSN261200611002C 200-200513434 TO 1 and 223-01-2460 to 27 between the National Academy of Sciences and the National Cancer Institute the Centers for Disease Control and Prevention and the Food and Drug Administration respectively. This study was also supported by the American Cancer Society the American Society of Clinical Oncology the Association of American Cancer Institutes and C-Change. Any opinions findings conclusions or recommendations expressed in this publication are those of the author s and do not necessarily reflect the view of the organizations or agencies that provided support for this project. International Standard Book Number-13 978-0-309-14575-6 International Standard Book Number-10 0-309-14575-9 Additional copies of this report are available from the National Academies Press 500 Fifth Street . Lockbox 285 Washington DC 20055 800 624-6242 or 202 334-3313 in the Washington metropolitan area Internet http . For more information about the Institute of Medicine visit the IOM home page at . Copyright 2010 by the National Academy of Sciences. All rights reserved. Printed in the United States of America The serpent has been a symbol of long life healing and .

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• Predictive Tests
• Increasing Complexity
• Clinical Implications
• Capture Clinical
• Value of Biomarkers
• Personalized Medicine
• BMC Anesthesiology
• Predictive biomarkers and imaging
• Post operative delirium
• Predicting post operative delirium
• BMC Geriatrics
• Cardiovascular diseases
• Patient readmission
• Predictive value of tests
• Risk assessment
• Functional impairment
• Personalized treatment options in dermatology
• Innovative therapeutics
• Personalized therapy for nonmelanoma
• Topical steroids
• Targeted therapies
• Targeted therapy
• Non small cell lung cancer
• Personalized medicine for effective treatment
• Targeted therapeutic drugs is reviewed
• Autoinfl ammatory syndromes
• Clinical heterogeneity
• Bullous diseases
• BMC Cancer
• Oral squamous cell carcinoma
• Personalized precision medicine
• Systemic biomarker models
• Biomarker discovery
• Computational personalized medicine
• Cancer research
• Omics data era
• Big picture
• Drug response prediction based
• BMC Genomics
• Precision medicine
• Genomic medicine
• Individualized medicine
• Evidence based medicine
• Stratified medicine
• Feeding Influences
• Weight of Children
• Breastfeeding Reduce
• Childhood Obesity
• Waist Circumference
• Children and Adolescents
• Braunwalds heart disease
• A textbook of cardiovascular medicine
• Fundamentals of cardiovascular disease
• Evaluation of the patient
• Heart failure
• Sudden death and syncope
• BMC Pulmonary Medicine
• Lung ultrasound
• Ultrasounds interact
• Cost effectiveness analysis
• Breast cancer
• Adjuvant chemotherapy
• Decision analysis
• Medical Innovations
• Finding Value
• General Observations
• Genomic Innovation
• Clinical Practice
• Progesterone Resistance
• Resistance and Targeting
• Progesterone Receptors
• Therapeutic Approach
• Approach to Endometriosis
• Endometriosis
• Genetics in medicine
• Developmental genetics
• Birth defects
• Cancer genetics and genomics
• Genetic counseling
• Prenatal diagnosis and screening
• Personalized health care
• Cystic fibrosis
• Health care analytics
• Health care delivery
• Mixed methods
• Statistical learning
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• patient agrees
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• information and support
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• Maillard Reaction
• pioneering discovery
• combat infections
• genes including Toll
• different non linear
• optimization techniques
• illegal adulterant
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• Spectrometry Data
• Clinical Proteomics
• Biomedical Applications
• Virtual Screening
• Molecular Medicine
• Virtual Human
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• Prevention and Future
• Behavioral and Psychosocial
• Obesity and Quality
• Diverse Ethnicity
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• Based Solutions
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