TAILIEUCHUNG - Health Risks from Dioxin and Related Compounds: Evaluation of the EPA Reassessment

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), also called dioxin, is among the most toxic anthropogenic substance ever identified. TCDD and a number of similar polychlorinated dioxins, dibenzofurans, and coplanar polychlorinated biphenyls (dioxin-like compounds [DLCs]) have been the subject of intense scientific research and frequently controversial environmental and health policies. Animal studies have demonstrated potent effects of TCDD, other dioxins, and many DLCs on tumor development, birth defects, reproductive abnormalities, immune dysfunction, dermatological disorders, and a plethora of other adverse effects | Health Risks from Dioxin and Related Compounds Evaluation of the EPA Reassessment http catalog Health Risks from Dioxin and Related Compounds Evaluation of the EPA Reassessment Committee on EPA s Exposure and Human Health Reassessment of TCDD and Related Compounds Board on Environmental Studies and Toxicology Division on Earth and Life Studies NATIONAL RESEARCH COUNCIL OF THE NATIONAL ACADEMIES THE NATIONAL ACADEMIES PRESS Washington DC Copyright National Academy of Sciences. All rights reserved. Health Risks from Dioxin and Related Compounds Evaluation of the EPA Reassessment http catalog THE NATIONAL ACADEMIES PRESS 500 Fifth Street . Washington DC 20001 NOTICE The project that is the subject of this report was approved by the Governing Board of the National Research Council whose members are drawn from the councils of the National Academy of Sciences the National Academy of Engineering and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance. This project was supported by Contract No. 68-C-03-081 between the National Academy of Sciences and the . Environmental Protection Agency. Any opinions findings conclusions or recommendations expressed in this publication are those of the author s and do not necessarily reflect the view of the organizations or agencies that provided support for this project. International Standard Book Number-10 0-309-10258-8 Book International Standard Book Number-13 978-0-309-10258-2 Book International Standard Book Number-10 0-309-66273-7 PDF International Standard Book Number-13 978-0-309-66273-4 PDF Library of Congress Control Number 2006933608 Additional copies of this report are available from The National Academies Press 500 Fifth Street NW Box 285 Washington DC 20055 800-624-6242 202-334-3313 in the Washington metropolitan area http Copyright 2006

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