TAILIEUCHUNG - Gene Therapy of Cancer Methods and Protocols

The molecular definition of tumor antigens, costimulatory signals, and the possibility to genetically engineer tumor cells as well as simple protocols for efficient isolation and preparation of dendritic cells (DC) renew the interest in tumor immunotherapy and vaccination, in particular. Engineering of tumor cells with the gene of a particular cytokine is a way of releasing that cytokine at the tumor site. In contrast to bolus administration, it provides a constant supply of cytokine. | M E T H O D S I N M O L E C U L A R M E D I C I N ETM Gene Therapy bijCancer Methods and Protocols Edited by 0 fe Wolfgang JWalther Ulrike Stein 57 A Gene Therapy of Cancer M E T H O D S I N M O L E C U L A R M E D I C I N ETM John M. Walker Series Editor 40. Diagnostic and Therapeutic Antibodies edited by Andrew J. T. George and Catherine E. Urch 2000 39. Ovarian Cancer Methods and Protocols edited by John M. s. Bartlett 2000 38. Aging Methods and Protocols edited by Yvonne A. Barnett and Christopher P. Barnett 2000 37. Electrically Mediated Delivery of Molecules to Cells edited by Mark J. Jaroszeski Richard Heller and Richard Gilbert 2000 36. Septic Shock Methods and Protocols edited by Thomas J. Evans 2000 35. Gene Therapy of Cancer Methods and Protocols edited by Wolfgang Walther and Ulrike Stein 2000 34. Rotavirus Methods and Protocols edited by James Gray and Ulrich Desselberger 2000 33. Cytomegalovirus Protocols edited by John Sinclair 2000 32. Alzheimer s Disease Methods and Protocols edited by Nigel M. Hooper 1999 31. Hemostasis and Thrombosis Protocols Methods in Molecular Medicine edited by David J. Perry and K. John Pasi 1999 30. Vascular Disease Molecular Biology and Gene Therapy Protocols edited by Andrew H. Baker 1999 29. DNA Vaccines Methods and Protocols edited by Douglas B. Lowrie and Robert Whalen 1999 28. Cytotoxic Drug Resistance Mechanisms edited by Robert Brown and Uta Boger-Brown 1999 27. Clinical Applications of Capillary Electrophoresis edited by Stephen M. Palfrey 1999 26. Quantitative PCR Protocols edited by Bernd Kochanowski and Udo Reischl 1999 25. Drug Targeting edited by G. E. Francis and Cristina Delgado 1999 24. Antiviral Methods and Protocols edited by Derek Kinchington and Raymond F. Schinazi 1999 23. Peptidomimetics Protocols edited by Wieslaw M. Kazmierski 1999 22. Neurodegeneration Methods and Protocols edited by Jean Harry and Hugh A. Tilson 1999 21. Adenovirus Methods and Protocols edited by William s. M. Wold .

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