TAILIEUCHUNG - The Use of Mushroom Glucans and Proteoglycans in Cancer Treatment

We first highlight psychological and psychosocial issues associated with breast can- cer, and then underscore specific psychosocial variables that may play a role in the dis- ease. Further, we bring to light the current literature of psychosocial interventions for patients with cancer. We then introduce preliminary research from an on-going study funded by the National Cancer Institute (NCI). This is a pilot study intended to explore psychosocial factors and quality of life, preparatory to embarking on a larger scale, long- term study. Finally, we discuss clinical implications in an attempt to lend greater under- standing to the complexities surrounding the relationship between quality of life and psychosocial issues. | The Use of Mushroom Glucans and Proteoglycans in Cancer Treatment by Parris M. Kidd PhD Abstract Immunoceuticals can be considered as substances having immunotherapeutic efficacy when taken orally. More than 50 mushroom species have yielded potential immunoceuticals that exhibit anticancer activity in vitro or in animal models and of these six have been investigated in human cancers. All are non-toxic and very well tolerated. Lentinan and schizophyllan have little oral activity. Active Hexose Correlated Compound AHCC is poorly defined but has shown early clinical promise. Maitake D-Fraction has limited proof of clinical efficacy to date but controlled research is underway. Two proteoglycans from Coriotus versicolor - PSK Polysaccharide-K and PSP Polysaccharide-Peptide - have demonstrated the most promise. In Japanese trials since 1970 PSK significantly extended survival at five years or beyond in cancers of the stomach colon-rectum esophagus nasopharynx and lung non-small cell types and in a HLA B40-positive breast cancer subset. PSP was subjected to Phase II and Phase III trials in China. In double-blind trials PSP significantly extended five-year survival in esophageal cancer. PSP significantly improved quality of life provided substantial pain relief and enhanced immune status in 70-97 percent of patients with cancers of the stomach esophagus lung ovary and cervix. PSK and PSP boosted immune cell production ameliorated chemotherapy symptoms and enhanced tumor infiltration by dendritic and cytotoxic T-cells. Their extremely high tolerability proven benefits to survival and quality of life and compatibility with chemotherapy and radiation therapy makes them well suited for cancer management regimens. Altem Med Rev2000 5 1 4-27 Introduction As the new millennium dawns humanity continues to strive for longer lifespan and better quality of life. But the disease of cancer continues to be the scourge of humanity being a leading cause of early death and resistant to .

• Y học thường thức
• Nested Case–Control
• Resistance and Targeting
• Progesterone Receptors
• Involvement
• Prostaglandins
• Pathophysiology of Endometriosis
• BMC Pharmacology and Toxicolog
• Concentration level
• Concomitant medication
• Neurological consequences
• Including depressed consciousness
• BMC Cancer
• Body mass index
• Lung cancer
• Cancer related deaths worldwide
• Odds ratios
• Endometriosis
• Urinary Tract Endometriosis
• Diagnosis and Treatment
• Perineal Endometriosis
• Abdominopelvic Complications
• Complications of Endometriosis
• Genetic Polymorphisms
• Molecular Pathogenesis
• Pathogenesis of Endometriosis