TAILIEUCHUNG - Báo cáo sinh học: "A pericentric inversion of chromosome 4 in pigs"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: A pericentric inversion of chromosome 4 in pigs | 383 Genet Sei Evol 1997 29 383-394 Elsevier Inra Original article A pericentric inversion of chromosome 4 in pigs A Ducos1 A Pinton1 A Séguéla1 HM Berland1 MF Blanc1 A Darré2 p Pinton3 M Yerle3 R Darré1 1 Uro. Inra-ENVT de cytogénétique des populations animates Ecole nationale vétérinaire 23 chemin des Capelles 31076 Toulouse cedex 2 École nationale de formation agronomique Service de zootechnie 31326 Castanet-Tolosan cedex 3 Laboratoire de génétique cellulaire Institut national de la recherche agronomique Auzeville BP 27 31326 Castanet-Tolosan cedex France Received 11 December 1996 accepted 16 May 1997 Summary - The main French porcine artificial insemination centre recently decided to carry out a systematic chromosomal evaluation of the animals used for pure-breeding purposes. This practice has allowed the identification of a new pericentric inversion affecting chromosome 4 in four Large White boars originating from four different herds. The cytogenetic evaluation by means of the GTG-banding technique revealed an inversion of the pericentric part of the chromosome after double breaks the first one in the pale band of the long arm and the second one in the upper border of the dark band of the short arm. The chromosomal rearrangement could be described according to the standard nomenclature as 38 XY inv 4 pl4q23 . This interpretation has been confirmed by in situ hybridization of the cosmid BHT12 located on the band. This chromosomal abnormality has no significant effect on production or reproductive performance of carrier animal. A rather old and common origin of the abnormality is hypothesized. chromosome aberration pericentric inversion pig reproductive performance FISH Resume Inversion péricentrique du chromosome 4 chez le pore. Le principal centre frangais d insemination artificielle porcine a récemment decide de procéder à un contrôle chromosomique systématique de tous les verrats de races pures. Cette pratique a permis de mettre en evidence

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