TAILIEUCHUNG - Báo cáo khoa hoc:"SRY-related genes in the genome of the rice field eel (Monopterus albus)"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: SRY-related genes in the genome of the rice field eel (Monopterus albus) | 129 Genet Sei. Evol. 34 2002 129-137 INRA EDP Sciences 2002 DOI gse 2001008 Original article SRY-related genes in the genome of the rice field eel Monopterus albus Rongjia Zhoua Hanhua Chenga QuiYang Zhangb Yiqing Guoa Richard K. Cooperb TerreNce R. Tierschc a Department of Genetics and Center for Developmental BiologY College of Life Sciences Wuhan UniversitY Wuhan 430072 PR China b Department of VeterinarY Science Louisiana State UniversitY Agricultural Center Louisiana Agricultural Experiment Station Baton Rouge LA 70803 USA c Aquaculture Research Station Louisiana State UniversitY Agricultural Center Louisiana Agricultural Experiment Station Baton Rouge LA 70803 USA Received 4 December 2000 accepted 12 June 2001 Abstract - The mammalian sex determining gene SRY is the founding member of the new growing family of Sox SRY-like HMG-box gene genes. Sox genes encode transcription factors with diverse roles in development and a few of them are involved in sex determination and differentiation. We report here the existence of Sox genes in the rice field eel Monopterus albus and DNA sequence information of the HMG box region of five Sox genes. The Soxl Sox4 and Soxl4 genes do not have introns in the HMG box region. The Sox9 gene and Soxl7 gene which each have an intron in the conserved region show strong identity at the amino acid level with the corresponding genes of mammals and chickens. Similar structure and identity of the Sox9 and Soxl7 genes among mammals chickens and fish suggest that these genes have evolutionarily conserved roles potentially including sex determination and differentiation. fish Sox cloning sex determination 1. introduction The identification of the testis-determining gene on the mammalian Y chromosome has been one of the recent breakthroughs of developmental biology. This gene named sex-determining region Y SRY is responsible for initiating testis development during mammalian embryogenesis 1 19 20 25 27 . Sequence analysis of SRY .

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