TAILIEUCHUNG - Báo cáo khoa hoc:"On the precision of estimation of genetic distance"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: On the precision of estimation of genetic distance | 457 Genet. Sei. Evol. 31 1999 457-464 Inra Elsevier Paris Original article On the precision of estimation of genetic distance Jean-Louis Foulleya William G. Hillb a Station de génétique quantitative et appliquée Institut national de la recherche agronomique 78352 Jouy-en-Josas cedex France b Institute of Cell Animal and Population Biology The University of Edinburgh Edinburgh EH9 3JT UK Received 26 April 1999 accepted 15 September 1999 Abstract - This article gives a formal proof of a formula for the precision of estimated genetic distances proposed by Barker et al. which can be used in designing experimental sampling programmes. The derivation is given in the general multi-allelic case using the Sanghvi distance. Two sources of sampling are considered . i among individuals or gametes within locus and ii among loci within populations Distribution assumptions about gene frequencies are discussed especially the normal used in Barker et al. versus the Dirichlet via simulation. Inra Elsevier Paris genetic distance estimation precision Dirichlet Résumé A propos de la precision de 1 estimation des distances génétiques. Cet article présente une demonstration formelle d une formule de Barker et al. donnant la precision de 1 estimation de distances génétiques à des fins de planification experimentale. Cette demonstration est faite dans le cas general multiallélique sur la base de la distance de Sanghvi. Deux sources d echantillonnage sont considérées à savoir i au niveau des individus ou gametes intra-locus et ii entre loci intrapopulations. Les hypotheses sur les lois des frequences géniques sont discutées via quelques simulations en particulier celle de la loi Normale adoptee par Barker et al. par rapport à la loi de Dirichlet Inra Elsevier Paris distance génétique estimation precision I Dirichlet 1. INTRODUCTION In a report to the FAO Barker et al. 2 proposed a formula to express the standard error of an estimate of the genetic distance d which was intended .

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