TAILIEUCHUNG - The Breast Cancer Epidemic: Modeling and Forecasts Based on Abortion and Other Risk Factors

Vaccinating girls and women before sexual debut, and therefore before exposure to HPV infection, provides an excellent opportunity to decrease the incidence of cervical cancer over time. As these vaccines protect against HPV types responsible for about 70% of cervical cancers, there will be a continued need to screen women who have been vaccinated as well as those who have not been vaccinated. Therefore, a comprehensive approach to cervical cancer prevention and control should involve vaccinating girls and women before sexual debut, and screening women for precancerous lesions and treatment before progression to invasive disease | The Breast Cancer Epidemic Modeling and Forecasts Based on Abortion and Other Risk Factors Patrick S. Carroll . ABSTRACT Using national cancer registration dataforfemale breast cancer incidence in eight European countries England Wales Scotland Northern Ireland the Irish Republic Sweden the Czech Republic Finland and Denmark for which there is also comprehensive data on abortion incidence trends are examined and future trends predicted. Seven reproductive risk factors are considered as possible explanatory variables. Induced abortion is found to be the best predictor and fertility is also a useful predictor. Forecasts are made using a linear regression model with these explanatory variables. Previous forecasts using the same model and incidence data for years through 1997 for England Wales are compared with numbers of cancers observed in years from 1998-2004 in an Appendix. The forecast predicted of the cancers observed in 2003 and of those observed in 2004. The Challenge ofAbortion for Epidemiologists in Female Breast Cancer Research It is difficult for epidemiologists to discover women s abortion history. In any study the numbers of women who have had abortions maybe National data on abortions in most countries tends to be deficient with abortions underreported. Official abortion statistics in the United States2 and France3 are known to understate the numbers of legal induced abortions. The countries considered in this study are believed to have nearly complete official abortion counts. The long lag time for the development of breast cancer magnifies the problem. The average age of diagnosis is over 60 while most abortions and live births occur at ages under 30. The modern increase in breast cancer incidence is obvious at ages over 45 4 and Figure 1 for England Wales shows the increase is small below age 45. Abortion did not become legal in most Western countries until the 1970s and earlier abortions among older women are not .

• Y học thường thức
• Cervical Cancer
• Bacterial Infections
• Chlamydia trachomatis
• Medical and Surgical
• Induced Abortion
• Post Abortion
• BMC Cancer
• Cervical intraepithelial neoplasia
• Cervical cytology
• High risk human papillomavirus
• Quality control
• A review of cervical cancer incidence
• Cervical cancer incidence
• HPV infection
• Sexually acquired infections
• Knowledge and attitude
• Cervical screening test
• Cervical cancer screening
• Attitude related
• Convenient sampling method
• E cadherin
• Therapeutic schemes
• Human papillomavirus
• Cervical dysplasia
• Organised cervical screening
• Mortality rates
• Annual percent change
• Single nucleotide polymorphisms
• Chinese population
• Epigenetic regulator
• Cancer deaths
• Cervical carcinogenesis
• Human papilloma virus
• Cervical cancer prevention
• Treatment in low
• Resource settings
• History cervical cancer
• High grade cervical dysplasia
• Atypical squamous cell
• Cervical cytological diagnosis
• Women’s knowledge
• Total knowledge score
• Screening willingness
• Tumor history
• Health belief model
• HIV positive women
• Cancer progression
• Cancer stem cells
• Cell lines
• Low passage
• Cross sectional study
• Multivariate analyses
• Cervical cancer cells
• Cell Counting Kit 8
• Quantitative real time polymerase chain reaction
• Tumor diseases
• TNF α
• Healthy controls
• Interferon gamma
• Treatment response
• Advanced squamous cervical cancer
• Antitumor therapy failure
• Concurrent chemotherapy
• Overall survival
• Cell proliferation 4
• Progression free survival
• Cisplatin based chemotherapy
• Advanced cervical cancer
• RNA seq
• Alternative splicing
• Cervical carcinoma
• Diabetes mellitus
• Neoadjuvant chemotherapy
• Locally advanced cervical cancer
• Cervical cancer stem cells
• Corresponding parental cells
• Sphere formation
• Non coding RNA molecules
• Chromosomal instability
• Despite treatment
• Distant metastasis
• TCGA cervical cancer
• Cross sectional
• Awareness of cervical cancer
• HPV vaccine among screening women