TAILIEUCHUNG - Chapter 176. Molluscum Contagiosum, Monkeypox, and Other Poxviruses, Excluding Smallpox Virus

The poxvirus family includes a large number of related DNA viruses that infect various vertebrate hosts. The poxviruses responsible for infections in humans, along with the main manifestations of these infections, are listed in Table 176-1. Infections with orthopoxviruses—., smallpox (variola major) virus (Chap. 214) or the zoonotic monkeypox virus—can result in systemic, potentially lethal human disease. Other poxvirus infections cause primarily localized skin disease in humans. Table 176-1 Poxviruses and Human Infections Genus Orthopoxvirus Species Variolaa Monkeypox Vaccinia Cowpox Molluscipoxvirus Molluscum contagiosum Parapoxvirus Orf Pseudocowpox Tanapox Human Disease Smallpox, systemic Smallpox-like, systemic Local pox lesion, occasionally systemic Local. | Chapter 176. Molluscum Contagiosum Monkeypox and Other Poxviruses Excluding Smallpox Virus Introduction The poxvirus family includes a large number of related DNA viruses that infect various vertebrate hosts. The poxviruses responsible for infections in humans along with the main manifestations of these infections are listed in Table 176-1. Infections with orthopoxviruses . smallpox variola major virus Chap. 214 or the zoonotic monkeypox virus can result in systemic potentially lethal human disease. Other poxvirus infections cause primarily localized skin disease in humans. Table 176-1 Poxviruses and Human Infections Genus Species Orthopoxvirus Variolaa Monkeypox Vaccinia Cowpox Molluscipoxvirus Molluscum contagiosum Parapoxvirus Orf Pseudocowpox Yatapoxvirus Tanapox Human Disease Smallpox systemic Smallpox-like systemic Local pox lesion occasionally systemic Local pox lesions Molluscum contagiosum multiple cutaneous lesions Contagious pustular dermatitis local pox lesions Milker s nodule local pox lesions Local pox lesions aSee Chap. 214. Molluscum Contagiosum Molluscum contagiosum virus is an obligate human pathogen that causes distinctive proliferative skin lesions. These lesions measure 2-5 mm in diameter and are pearly flesh-colored and umbilicated with a characteristic dimple at the center Fig. 176-1 . A relative lack of inflammation and necrosis distinguishes these proliferative lesions from other poxvirus lesions. Lesions may be found singly or in clusters anywhere on the body except on the palms and soles and may be associated with an eczematous rash. Figure 176-1 Sourc Fauci AS Kasper DL fcriufiwald Ej Hauser SIUf Lôrìgo DL_. JimMflh JL_. Lcsealzo J i amjw i tfraxzp tJ ử nteroj 17th Edition http i fwww. access medicine. con-1 Copyright Th Mc 3ri w Hill Companies J Inc. All rigihts reserved- Molluscum contagiosum is a cutaneous poxvirus infection characterized by multiple umbilicated flesh-colored or hypopigmented papules. Molluscum .

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