TAILIEUCHUNG - báo cáo hóa học: " e differential mediating effects of pain and depression on the physical and mental dimension of quality of life in Hong Kong Chinese adults"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : e differential mediating effects of pain and depression on the physical and mental dimension of quality of life in Hong Kong Chinese adults | Wong et al. Health and Quality of Life Outcomes 2010 8 1 http content 8 1 1 HEALTH AND QUALITY of life outcomes SHORT REPORT Open Access The differential mediating effects of pain and depression on the physical and mental dimension of quality of life in Hong Kong Chinese adults Wing S Wong1 Simon TM Chan2 Vivian BK Fung3 Richard Fielding3 Abstract Objective The impact of pain and depression on health-related quality of life QoL is widely investigated yet the pain-depression interactions on QoL remain unclear. This study aims to examine the pain-depression-QoL mediation link. Methods Pain severity were assessed in a sample of Chinese professional teachers n 385 . The subjects were also assessed on depressive symptoms and QoL. Regression models were fitted to evaluate the pain-depression-QoL relationships. Results About 44 of the sample had 3-5 painful areas in the past 3 months. Shoulder pain 60 and headache 53 were common painful areas. The results of regression analyses showed that pain mediated the effects of depression on the mental aspect of QoL standardized b Sobel test z p whereas depression mediated the effects of pain on the physical aspect of QoL standardized b Sobel test z p . Conclusions Our study offered tentative evidence that pain and depression impacted differently on the mental and physical aspect of QoL. As these findings were based on a Chinese teacher sample future studies should employ more representative samples across cultures to verify the present data. Introduction Chronic pain and depression are often co-morbid. The prevalence of depression among pain patients ranges from 10 1 to 100 2 whereas about 30 3 to 100 4 of depressed patients report pain. The nature and mechanism of the pain-depression association has been widely investigated 5 yet remain largely inconclusive. Research on the causal direction s of the paindepression relationship has focused on three major lines of investigation 6

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