TAILIEUCHUNG - Báo cáo sinh học: "Developmental time at which spontaneous, X-ray-induced and EMS-induced recessive lethal mutations become effective in Drosophila melanogaster"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Developmental time at which spontaneous, X-ray-induced and EMS-induced recessive lethal mutations become effective in Drosophila melanogaster | Genet Set Evol 1992 24 473-486 Elsevier INRA 1FE7ÍÌ. 1993 473 Original article Developmental time at which spontaneous X-ray-induced and EMS-induced recessive lethal mutations become effective in Drosophila melanogaster YE Kwon D Sperlich University of Tubingen Department of Population Genetics Auf der Morgenstelle 28 D-7Ặ00 Tubingen Germany Received 6 November 1991 accepted 7 September 1992 Summary - Allozyme markers phosphoglucomutase Pgm and alcoholdehydrogenase Adh were used to determine the developmental time at which recessive lethal mutations of Drosophila melanogaster become effective. X-ray and EMS ethyl-methane-sulfonate induced mutations proved effective at earlier developmental stages on the average than natural lethal mutations of spontaneous origin. In competition experiments with X-ray induced lethal chromosomes kept in balance with lethal marker chromosomes late lethal mutations proved superior to early lethal mutations. For EMS-induced lethal mutations this effect was not observed. Reasons for and consequence of these observations are discussed. lethal mutation genetic load Drosophila melanogaster I chromosomal arrangement Resume - Moment du développement auquel les mutations létales récessives spon-tanées ou induites par rayons X OU par EMS deviennent effectives chez Drosophila melanogaster. Des marqueurs enzymatiques phosphoglucomutase et alcooldéshydrogénase ont été utilises pour determiner le moment du développement auquel les mutations létales récessives de Drosophila melanogaster deviennent effectives. Les mutations induites par rayons X OU par EMS éthyl-méthane-sulỊonate se sont montrées en moyenne effectives à des stades de développement plus précoces que les mutations létales d origine spontanée. Dans des experiences de competition entre des chromosomes porteurs de létaux induits par rayons X maintenus en équilibre avec chromosomes porteurs de marqueurs létaux les mutations létales tardives se sont montrées supérieures aux mutations .

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