TAILIEUCHUNG - báo cáo hóa học:" Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study | Journal of Translational Medicine BioMed Central Research Static platelet adhesion flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease a randomised cross-over study Andreas C Eriksson 1 Lena Jonasson2 Tomas L Lindahl3 Bo Hedback2 and Per A Whiss1 Open Access Address 1Division of Drug Research Pharmacology Department of Medical and Health Sciences Linkõping University SE-581 85 Linkõping Sweden 2Division of Cardiology Department of Medical and Health Sciences Linkõping University SE-581 85 Linkõping Sweden and 3Department of Clinical Chemistry Laboratory Medicine University Hospital SE-581 85 Linkõping Sweden Email Andreas C Eriksson - Lena Jonasson - Tomas L Lindahl - Bo Hedback - Per AWhiss - Corresponding author Published 9 June 2009 Received 27 February 2009 Journal of Translational Medicine 2009 7 42 doi 1479-5876-7-42 Accepted 9 June 2009 This article is available from http content 7 1 42 2009 Eriksson et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Despite the use of anti-platelet agents such as acetylsalicylic acid ASA and clopidogrel in coronary heart disease some patients continue to suffer from atherothrombosis. This has stimulated development of platelet function assays to monitor treatment effects. However it is still not recommended to change treatment based on results from platelet function assays. This study aimed to evaluate the capacity of a static platelet adhesion assay to detect platelet inhibiting effects of ASA and clopidogrel. The adhesion assay measures .

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