TAILIEUCHUNG - Báo cáo sinh học: " Estimated breeding values and association mapping for persistency and total milk yield using natural cubic smoothing splines"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Estimated breeding values and association mapping for persistency and total milk yield using natural cubic smoothing splines | Genetics Selection Evolution BioMed Zentral Research Open Access Estimated breeding values and association mapping for persistency and total milk yield using natural cubic smoothing splines Klara L Verbyla 1 and Arunas P Verbyla2 3 Addresses 1Victorian Department of Primary Industries Bundoora VIC 3083 Australia 2School of Agriculture Food and Wine The University of Adelaide Adelaide SA 5005 Australia and Mathematical and Information Sciences CSIRO Urrbrae SA 5064 Australia E-mail Klara LVerbyla - Arunas P Verbyla - Corresponding author Published 05 November 2009 Received 23 March 2009 Genetics Selection Evolution 2009 41 48 doi 1297-9686-41-48 Accepted 5 November 2009 This article is available from http content 41 1 48 2009 Verbyla and Verbyla licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background For dairy producers a reliable description of lactation curves is a valuable tool for management and selection. From a breeding and production viewpoint milk yield persistency and total milk yield are important traits. Understanding the genetic drivers for the phenotypic variation of both these traits could provide a means for improving these traits in commercial production. Methods It has been shown that Natural Cubic Smoothing Splines NCSS can model the features of lactation curves with greater flexibility than the traditional parametric methods. NCSS were used to model the sire effect on the lactation curves of cows. The sire solutions for persistency and total milk yield were derived using NCSS and a whole-genome approach based on a hierarchical model was developed for a large association study using single nucleotide .

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