TAILIEUCHUNG - Báo cáo sinh học: "Testing strategies for genomic selection in aquaculture breeding programs"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Testing strategies for genomic selection in aquaculture breeding programs | Genetics Selection Evolution BioMed Central Research Testing strategies for genomic selection in aquaculture breeding programs Anna K Sonesson 1 and Theo HE Meuwissen 2 Open Access Address 1Nofima Marine AS . Box 5010 1432 Ảs Norway and 2University of Life Sciences . Box 5003 1432 Ảs Norway Email Anna K Sonesson - Theo HE Meuwissen - Corresponding author fEqual contributors Published 30 June 2009 Received 5 May 2009 Genetics Selection Evolution 2009 41 37 doi 1297-9686-41-37 Accepted 30 June 2009 This article is available from http content 41 1 37 2009 Sonesson and Meuwissen licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Genomic selection is a selection method where effects of dense genetic markers are first estimated in a test population and later used to predict breeding values of selection candidates. The aim of this paper was to investigate genetic gains inbreeding and the accuracy of selection in a general genomic selection scheme for aquaculture where the test population consists of sibs of the candidates. Methods The selection scheme started after simulating 4000 generations in a Fisher-Wright population with a size of 1000 to create a founder population. The basic scheme had 3000 selection candidates 3000 tested sibs of the candidates 100 full-sib families a trait heritability of and a marker density of M. Variants of this scheme were also analysed. Results The accuracy of selection in generation 5 was for the basic scheme when the sib-testing was performed every generation. The accuracy was hardly reduced by selection probably because the increased frequency of favourable alleles compensated for the .

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